Transplants Facilitated

The transplants facilitated by SCBB have been for haematological diseases categorised into blood cancers and blood disorders for adults and children in Singapore and around the world. In paediatric and adult patients, acute myeloid leukaemia (AML) and acute lymphoblastic leukaemia (ALL) are the top two blood cancers. 

A total of 74% of the patients had blood cancers and 26% had other disorders of the blood and immune system.  The SCBB distributed the CBUs through BMDP Programme (Singapore), the US' NDMP and other registries that have searched SCBB directly.

SCBB has facilitated transplants for over 30 blood related conditions.  For adults, 91% of these were blood cancers while the rest were for other serious blood disorders.  In children, 53% were for blood cancers and 47% for serious blood disorders. The list of blood conditions facilitated using SCBB’s CBUs are as follows:-

  1. Acute Lymphoblastic Leukaemia (ALL)
  2. Acute Myeloid Leukaemia (AML)
  3. Chronic Myelogenous Leukaemia (CML)
  4. Chronic Lymphocytic Leukaemia (CLL)
  5. Adrenoleukodystrophy (ALD)
  6. Bilineage Acute Leukaemia
  7. Acute Non-lymphocytic Leukaemia (ANLL)
  8. Juvenile Chronic Myelogenous Leukaemia
  9. Granulocyte Sarcoma
  10. Non-Hodgkin's Lymphoma (NHL)
  11. NK T-cell Lymphoma
  12. Hodgkin’s Lymphoma
  13. NK Cell Leukemia
  14. Lymphoma
  15. Multiple Myeloma
  16. Subcutaneous Panniculitic T Cell Lymphoma
  17. Congenital Dyserythropoietic Anaemia
  18. Neutropenia
  19. Fanconi’s Anaemia
  20. Hyper IGM Syndrome
  21. Myelodysplastic Syndrome
  22. Severe Combined Immuno-Deficiency  (SCID)
  23. Thalassemia Major
  24. Hemophagoctic Lymphohistiocytosis
  25. Systemic Mastocytosis
  26. Hunter’s Syndrome (MPS II)
  27. Lupus Erythematosus
  28. Omenn's Syndrome
  29. Chronic Granulomatous Disease (CGD)
  30. Myelofibro Myeloid Metaplasia 
  31. Wiskott-Aldrich Syndrome
  32. Metachromatic Leukodystrophy
  33. Osteopetrosis
  34. Aplastic Anaemia
SCBB encourages patients with the disease indicated above to discuss their condition with their haematologist and transplant physician, as not all patients will benefit from a cord blood transplant.